Dogs don't have malicious thoughts and do things out of spite.
Your dog likely does not know what she can and cannot chew on. Like Carriana said, bitter apple should be a deterrent not a punishment.
I would recommend that if you don't want her to chew on something, you should move it out of her reach. I can share what I have done with my boy, I moved everything "inappropriate" out of his reach. I did not chase him when he had something he shouldn't have. I also worked on the "leave it" command. It will take consistency. She is not running away from you because she is being spiteful, she is running because she has something that she thinks is fun, and you want to take that away from her. You running after her makes it a game.
Stop chasing her, and spraying bitter apple in her mouth. If she cannot be trusted alone then crate her when she is not being watched, and give her something appropriate while she is in there, or put a lead on her and tie it to yourself, so that she is never out of your site. Being alone is a privilege she has shown you that she can not handle that privilege.
Sent from Petguide.com Free App