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dont really see the point in doing it before vaccinations , since they are done so young , I wouldnt give young pups anything if they are too young for vaccinations , JMO.
 

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from reading it, it looks like a waste of money as it does nothing to prevent parvo. It says it treat symptoms but if the dog is sick with parvo this will not help. Also preventing vomiting or lose stool will do nothing in preparation for the vaccine. waste of money IMO

You can start puppies @ 4wks with a Parvo ONLY and it can help boost the effectiveness of later vaccines but following a regular protocol can be just as effective.
 
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